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Review
. 2017 Oct;29(10):642-652.
doi: 10.1016/j.clon.2017.06.003. Epub 2017 Jun 29.

Neoadjuvant Therapy in Early Breast Cancer: Treatment Considerations and Common Debates in Practice

H Cain  1 , I R Macpherson  2 , M Beresford  3 , S E Pinder  4 , J Pong  5 , J M Dixon  6
Affiliations
Free article
Review

Neoadjuvant Therapy in Early Breast Cancer: Treatment Considerations and Common Debates in Practice

H Cain et al. Clin Oncol (R Coll Radiol). 2017 Oct.
Free article

Abstract

Neoadjuvant treatment offers a number of benefits for patients with early breast cancer, and is an important option for consideration by multidisciplinary teams. Despite literature showing its efficacy, the use of neoadjuvant therapy varies widely. Here we discuss the clinical evidence supporting the use of neoadjuvant therapy in early stage breast cancer, including patient selection, monitoring response, surgery and radiotherapy considerations, with the aim of assisting multidisciplinary teams to determine patient suitability for neoadjuvant treatment.

Keywords: Breast cancer; chemotherapy; endocrine therapy; multidisciplinary; neoadjuvant treatment; patient management.

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