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Case Reports
. 2017 Jul;30(3):348-350.
doi: 10.1080/08998280.2017.11929644.

Olmesartan-associated enteropathy

Vivian S Ebrahim  1 , Jason Martin  1 , Stacey Murthy  1 , Elizabeth Odstrcil  1 , He Huang  1 , Daniel Polter  1
Affiliations
Case Reports

Olmesartan-associated enteropathy

Vivian S Ebrahim et al. Proc (Bayl Univ Med Cent). 2017 Jul.

Abstract

Olmesartan, an angiotensin-receptor blocker frequently prescribed for hypertension, has been commercially available since 2002. In 2012, olmesartan-associated enteropathy was described, and the Food and Drug Administration now requires a black-box warning for olmesartan regarding severe diarrhea. The disorder can be life-threatening and often requires hospitalization. We present three cases that represent different aspects of this disorder, as well as some unusual features.

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Figures

Figure 1.
Figure 1.
Biopsy in Case 1 showing (a) collagenous gastritis (hematoxylin and eosin [H&E] stain, 200×) and (b) collagenous and lymphocytic colitis (H&E, 20×). (c) Duodenal biopsy in Case 3 showing severe villous atrophy (H&E, 100×).
See this image and copyright information in PMC

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