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Review
. 2017 Jul;18(7):45.
doi: 10.1007/s11864-017-0483-z.

Clinical Impact of the 2016 Update to the WHO Lymphoma Classification

Ryan C Lynch  1 , Dita Gratzinger  2 , Ranjana H Advani  3   4
Affiliations
Review

Clinical Impact of the 2016 Update to the WHO Lymphoma Classification

Ryan C Lynch et al. Curr Treat Options Oncol. 2017 Jul.

Erratum in

Abstract

The 2016 revision of the WHO classification of lymphoid neoplasms includes new entities along with a clearer definition of provisional and definitive subtypes based on better understanding of the molecular drivers of lymphomas. These changes impact current treatment paradigms and provide a framework for future clinical trials. Additionally, this update recognizes several premalignant or predominantly indolent entities and underscores the importance of avoiding unnecessarily aggressive treatment in the latter subsets.

Keywords: ALK-negative anaplastic large cell lymphoma (ALCL); BCL6 translocations; Burkitt lymphoma; Chronic lymphocytic leukemia (CLL); Diffuse large B cell lymphoma (DLBCL); Double hit lymphoma; Follicular lymphoma; High grade B cell lymphoma NOS; Lymphoplasmacytic lymphoma; Mantle cell lymphoma; Non-Hodgkin lymphoma; Waldenström macroglobulinemia.

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