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. 2017 May 23;4(3):ofx102.
doi: 10.1093/ofid/ofx102. eCollection 2017 Summer.

Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users

Deanna J Buehrle  1 , Ryan K Shields  1 , Neel Shah  1 , Christopher Shoff  1 , Kathleen Sheridan  1
Affiliations

Risk Factors Associated With Outpatient Parenteral Antibiotic Therapy Program Failure Among Intravenous Drug Users

Deanna J Buehrle et al. Open Forum Infect Dis. .

Abstract

Sixty-one percent of intravenous drug users (IVDUs) who received outpatient parenteral antibiotic therapy (OPAT) failed treatment. Hospital readmission and adverse drug reactions occurred in 25%. By multivariate analysis, time since last IVDU was associated with failure (P = .04). Intravenous drug users requiring OPAT are at high risk for failure; additional studies are needed to explore alternatives.

Keywords: IVDA; IVDU; OPAT; outpatient antibiotics..

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