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. 2017 Jul;7(1):145-147.
doi: 10.3892/mco.2017.1264. Epub 2017 May 17.

Bilateral primary adrenal diffuse large B cell lymphoma without adrenal insufficiency: A case report and review of the literature

Peijie Chen  1   2 , Lu Jin  1   3 , Yu Yang  1 , Liangchao Ni  1 , Shangqi Yang  1 , Yongqing Lai  1
Affiliations

Bilateral primary adrenal diffuse large B cell lymphoma without adrenal insufficiency: A case report and review of the literature

Peijie Chen et al. Mol Clin Oncol. 2017 Jul.

Abstract

Primary adrenal lymphoma (PAL) is an infrequent malignant tumor, occurring in the bilateral adrenal glands as a mass in the majority of cases. The current study presents a case of bilateral primary adrenal diffuse large B cell lymphoma in a 52-year-old female patient, who presented with abdominal pain in the left lumbar region for ~2 weeks. Abdominal ultrasound examination and computed tomography scanning revealed a mass of 132×119×101 mm on the left adrenal gland and a mass of 53×27 mm on the right adrenal gland. A percutaneous biopsy was performed and histopathological examination further confirmed this lesion as diffuse large B cell lymphoma. The present study highlights the importance of early diagnosis of PAL, and performs a literature review of the subject.

Keywords: adrenal gland neoplasm; diffuse large B-cell lymphoma; non-Hodgkin lymphoma; primary adrenal lymphoma.

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Figures

Figure 1.
Figure 1.
Computed tomography images of adrenal masses prior to (A) and following (B-D) intravenous administration of contrast material. It revealed a mass of 132×119×101 mm on the left adrenal gland (asterisk) and a mass of 53×27 mm on the right adrenal gland (arrow).
Figure 2.
Figure 2.
Microscopy revealed diffuse large lymphoid cells following percutaneous biopsy of the left adrenal gland (H&E staining; left panel, magnification ×100; right panel, ×400).
See this image and copyright information in PMC

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