Raw milk consumption and other early-life farm exposures and adult pulmonary function in the Agricultural Lung Health Study
- PMID: 28689172
- PMCID: PMC5758444
- DOI: 10.1136/thoraxjnl-2017-210031
Raw milk consumption and other early-life farm exposures and adult pulmonary function in the Agricultural Lung Health Study
Abstract
Literature suggests that early exposure to the farming environment protects against atopy and asthma; few studies have examined pulmonary function. We evaluated associations between early-life farming exposures and pulmonary function in 3061 adults (mean age=63) from a US farming population using linear regression. Childhood raw milk consumption was associated with higher FEV1 (β=49.5 mL, 95% CI 2.8 to 96.1 mL, p=0.04) and FVC (β=66.2 mL, 95% CI 13.2 to 119.1 mL, p=0.01). We did not find appreciable associations with other early-life farming exposures. We report a novel association between raw milk consumption and higher pulmonary function that lasts into older adulthood.
Keywords: Allergic lung disease; Asthma Epidemiology; COPD epidemiology; Occupational Lung Disease; Respiratory Measurement.
© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Conflict of interest statement
Competing interests: None declared.
References
-
- von Mutius E, Vercelli D. Farm living: effects on childhood asthma and allergy. Nat Rev Immunol. 2010;10:861–868. - PubMed
-
- Braun-Fahrlander C, von Mutius E. Can farm milk consumption prevent allergic diseases? Clin Exp Allergy. 2011;41:29–35. - PubMed
-
- House JS, Wyss AB, Hoppin JA, Richards M, Long S, Umbach DM, Henneberger PK, Beane Freeman LE, Sandler DP, O’Connell E, Cummings C, London SJ. Early-life farm exposures and adult asthma and atopy in the Agricultural Lung Health Study. J Allergy Clin Immunol. 2016 Nov 12; doi: 10.1016/j.jaci.2016.09.036. - DOI - PMC - PubMed
-
- Campbell B, Raherison C, Lodge CJ, Lowe AJ, Gislason T, Heinrich J, Sunyer J, Gómez Real F, Norbäck D, Matheson MC, Wjst M, Dratva J, de Marco R, Jarvis D, Schlünssen V, Janson C, Leynaert B, Svanes C, Dharmage SC. The effects of growing up on a farm on adult lung function and allergic phenotypes: an international population-based study. Thorax. 2017;72(3):236–244. - PubMed
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