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. 2017 Jul 11;15(1):54.
doi: 10.1186/s12969-017-0182-0.

Cardiac findings in children with juvenile Dermatomyositis at disease presentation

Serdar Cantez  1 , Gil J Gross  2 , Ian MacLusky  3 , Brian M Feldman  4
Affiliations

Cardiac findings in children with juvenile Dermatomyositis at disease presentation

Serdar Cantez et al. Pediatr Rheumatol Online J. .

Abstract

Background: Juvenile Dermatomyositis (JDM) is a pediatric vasculopathy characterized primarily by skin and muscle involvement. Cardiac findings have been reported in children with JDM but have rarely been investigated in detail.

Methods: We aimed to describe the relevant clinical and laboratory cardiac findings of a cohort of patients with JDM, followed at one centre, at disease diagnosis.

Results: We performed a retrospective review of 105 patients with JDM, followed from 1991 to 2007. Six of 70 patients (9%, 6% of the entire cohort) had abnormal electrocardiographic (ECG) findings, while 26 of 54 patients (48%, 25% of the entire cohort) had abnormal echocardiographic (echo) findings. Many of these findings were either mild or unlikely to be a result of JDM.

Conclusions: Our findings suggest that cardiac abnormalities at JDM disease onset are frequently seen, but are rarely significant findings due to disease; however, JDM patients should be considered for screening for cardiac disease as late cardiac complications are well recognized.

Keywords: Heart disease; Juvenile dermatomyositis; Screening.

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Conflict of interest statement

Ethics approval and consent to participate

This study was approved by the Research Ethics Board at The Hospital for Sick Children, Toronto (REB #1000008690).

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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