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Review
. 2017 Jul-Sep;8(3):421-426.
doi: 10.4103/jnrp.jnrp_44_17.

Neuropsychiatric Manifestations of Scrub Typhus

Sanjay K Mahajan  1 , Sanyam K Mahajan  2
Affiliations
Review

Neuropsychiatric Manifestations of Scrub Typhus

Sanjay K Mahajan et al. J Neurosci Rural Pract. 2017 Jul-Sep.

Abstract

Scrub typhus is caused by Orientia tsutsugamushi characterized by focal or disseminated vasculitis and perivasculitis which may involve the lungs, heart, liver, spleen and central nervous system. It was thought to have been eradicated from India. Recently it is being reported from many areas of India. The clinical picture and severity of the symptoms varies widely. The neurological manifestations of scrub typhus are not uncommon but are diverse. Meningoencephalitis is classical manifestation of scrub typhus but cerebellitis, cranial nerve palsies, plexopathy, transverse myelitis, neuroleptic malignant syndrome and Guillan-Barré syndrome are other manifestations reported in literature. The availability of literature on the neurological manifestations of scrub typhus is limited to case reports mainly. This article reviews various neurological manifestations of scrub typhus reported in literature.

Keywords: Himachal Pradesh; meningoencephalitis; rickettsia; rickettsial diseases.

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Conflict of interest statement

There are no conflicts of interest.

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