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Review
. 2017 Apr 5:16:464-482.
doi: 10.17179/excli2017-182. eCollection 2017.

The role of magnesium sulfate in the intensive care unit

Yunes Panahi  1   2 , Mojtaba Mojtahedzadeh  2   3 , Atabak Najafi  4 , Mohammad Reza Ghaini  5 , Mohammad Abdollahi  6 , Mohammad Sharifzadeh  6 , Arezoo Ahmadi  4 , Seyyed Mahdi Rajaee  1 , Amirhossein Sahebkar  7
Affiliations
Review

The role of magnesium sulfate in the intensive care unit

Yunes Panahi et al. EXCLI J. .

Abstract

Magnesium (Mg) has been developed as a drug with various clinical uses. Mg is a key cation in physiological processes, and the homeostasis of this cation is crucial for the normal function of body organs. Magnesium sulfate (MgSO4) is a mineral pharmaceutical preparation of magnesium that is used as a neuroprotective agent. One rationale for the frequent use of MgSO4 in critical care is the high incidence of hypomagnesaemia in intensive care unit (ICU) patients. Correction of hypomagnesaemia along with the neuroprotective properties of MgSO4 has generated a wide application for MgSO4 in ICU.

Keywords: ICU; intensive care unit; magnesium sulfate; neuroprotection.

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Table 1
Table 1. Summary of clinical studies evaluating the role of magnesium sulfate (MgSO4) in critically ill patients
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