Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Jun 15;8(6):235-248.
doi: 10.4239/wjd.v8.i6.235.

Diabetes mellitus and stroke: A clinical update

Affiliations
Review

Diabetes mellitus and stroke: A clinical update

Nyo Nyo Tun et al. World J Diabetes. .

Abstract

Cardiovascular disease including stroke is a major complication that tremendously increases the morbidity and mortality in patients with diabetes mellitus (DM). DM poses about four times higher risk for stroke. Cardiometabolic risk factors including obesity, hypertension, and dyslipidaemia often co-exist in patients with DM that add on to stroke risk. Because of the strong association between DM and other stroke risk factors, physicians and diabetologists managing patients should have thorough understanding of these risk factors and management. This review is an evidence-based approach to the epidemiological aspects, pathophysiology, diagnostic work up and management algorithms for patients with diabetes and stroke.

Keywords: Cardiovascular disease; Diabetes mellitus; Glycaemic management; Metabolic memory; Stroke.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: None.

References

    1. International Diabetes Federation. IDF Diabetes Atlas - 7th Edition ([accessed 2016 Dec 11]) Available from: http://www.diabetesatlas.org/key-messages.html. - PubMed
    1. World Health Organization. Ageing and health (WHO, Geneva. 2015, [accessed. 2016. p. Dec 11]). Available from: http://www.who.int/mediacentre/factsheets/fs404/en/
    1. Dutton GR, Lewis CE. The Look AHEAD Trial: Implications for Lifestyle Intervention in Type 2 Diabetes Mellitus. Prog Cardiovasc Dis. 2015;58:69–75. - PMC - PubMed
    1. Maahs DM, Daniels SR, de Ferranti SD, Dichek HL, Flynn J, Goldstein BI, Kelly AS, Nadeau KJ, Martyn-Nemeth P, Osganian SK, et al. Cardiovascular disease risk factors in youth with diabetes mellitus: a scientific statement from the American Heart Association. Circulation. 2014;130:1532–1558. - PubMed
    1. Krishnamurthi RV, Feigin VL, Forouzanfar MH, Mensah GA, Connor M, Bennett DA, Moran AE, Sacco RL, Anderson LM, Truelsen T, et al. Global and regional burden of first-ever ischaemic and haemorrhagic stroke during 1990-2010: findings from the Global Burden of Disease Study 2010. Lancet Glob Health. 2013;1:e259–e281. - PMC - PubMed

LinkOut - more resources