Gating Ciliary Transport
- PMID: 28697332
- DOI: 10.1016/j.devcel.2017.06.016
Gating Ciliary Transport
Abstract
Cilia lack the ability to synthesize proteins and thus require dynamic transport. Reporting in this issue of Developmental Cell, Kanie et al. (2017) shed light on the mechanism of transport by implicating CEP19, which is associated with an autosomal-recessive obesity syndrome when mutated, in the triggering of intraflagellar transport.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.Dev Cell. 2017 Jul 10;42(1):22-36.e12. doi: 10.1016/j.devcel.2017.05.016. Epub 2017 Jun 15. Dev Cell. 2017. PMID: 28625565 Free PMC article.
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