Pseudomonas aeruginosa quorum sensing modulates immune responses: An updated review article
- PMID: 28698104
- DOI: 10.1016/j.imlet.2017.07.002
Pseudomonas aeruginosa quorum sensing modulates immune responses: An updated review article
Abstract
Pseudomonas aeruginosa is an opportunistic bacterium which induces some complications in immunocompromised patients. Pseudomonas aeruginosa is a quorum-sensing using bacterium which regulates its genes expression. The bacterium uses two famous pathways for quorum sensing entitled LasI/LasR and RhlI/RhlR systems. It has been documented that the bacteria which use quorum sensing are able to overcome immune responses. This review article aims to present recent information regarding the effects of Pseudomonas aeruginosa quorum sensing systems on the host immune responses.
Keywords: 3O-C12-HSL; C4-HSL; Immune system; Pseudomonas aeruginosa; Quorum sensing.
Copyright © 2017 European Federation of Immunological Societies. Published by Elsevier B.V. All rights reserved.
Similar articles
-
Pseudomonas aeruginosa quorum-sensing response in the absence of functional LasR and LasI proteins: the case of strain 148, a virulent dolphin isolate.FEMS Microbiol Lett. 2017 Jul 3;364(12). doi: 10.1093/femsle/fnx119. FEMS Microbiol Lett. 2017. PMID: 28591849
-
Inactivation of the quorum-sensing transcriptional regulators LasR or RhlR does not suppress the expression of virulence factors and the virulence of Pseudomonas aeruginosa PAO1.Microbiology (Reading). 2019 Apr;165(4):425-432. doi: 10.1099/mic.0.000778. Epub 2019 Feb 1. Microbiology (Reading). 2019. PMID: 30707095
-
The effect of specific rhlA-las-box mutations on DNA binding and gene activation by Pseudomonas aeruginosa quorum-sensing transcriptional regulators RhlR and LasR.FEMS Microbiol Lett. 2014 Jul;356(2):217-25. doi: 10.1111/1574-6968.12505. FEMS Microbiol Lett. 2014. PMID: 24935161
-
An evolving perspective on the Pseudomonas aeruginosa orphan quorum sensing regulator QscR.Front Cell Infect Microbiol. 2014 Oct 28;4:152. doi: 10.3389/fcimb.2014.00152. eCollection 2014. Front Cell Infect Microbiol. 2014. PMID: 25389523 Free PMC article. Review.
-
Pseudomonas aeruginosa biofilms: mechanisms of immune evasion.Adv Appl Microbiol. 2014;86:1-40. doi: 10.1016/B978-0-12-800262-9.00001-9. Adv Appl Microbiol. 2014. PMID: 24377853 Review.
Cited by
-
Surfactant phospholipids act as molecular switches for premature induction of quorum sensing-dependent virulence in Pseudomonas aeruginosa.Virulence. 2020 Dec;11(1):1090-1107. doi: 10.1080/21505594.2020.1809327. Virulence. 2020. PMID: 32842850 Free PMC article.
-
Impact of quorum sensing signaling molecules in gram-negative bacteria on host cells: current understanding and future perspectives.Gut Microbes. 2022 Jan-Dec;14(1):2039048. doi: 10.1080/19490976.2022.2039048. Gut Microbes. 2022. PMID: 35188058 Free PMC article. Review.
-
The P-Type ATPase PA1429 Regulates Quorum-Sensing Systems and Bacterial Virulence.Front Microbiol. 2017 Dec 7;8:2449. doi: 10.3389/fmicb.2017.02449. eCollection 2017. Front Microbiol. 2017. PMID: 29375491 Free PMC article.
-
Predatory bacteria can reduce Pseudomonas aeruginosa induced corneal perforation and proliferation in a rabbit keratitis model.Ocul Surf. 2023 Apr;28:254-261. doi: 10.1016/j.jtos.2023.05.002. Epub 2023 May 3. Ocul Surf. 2023. PMID: 37146902 Free PMC article.
-
Investigation of bioactive components responsible for the antibacterial and anti-biofilm activities of Caroxylon volkensii by LC-QTOF-MS/MS analysis and molecular docking.RSC Adv. 2024 Apr 9;14(16):11388-11399. doi: 10.1039/d4ra01646g. eCollection 2024 Apr 3. RSC Adv. 2024. PMID: 38595719 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
