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Case Reports
. 2017 May 20;5(3):344-348.
doi: 10.3889/oamjms.2017.044. eCollection 2017 Jun 15.

Primary Fallopian Tube Carcinoma: A Case Report and Literature Review

Meral Rexhepi  1 , Elizabeta Trajkovska  2 , Hysni Ismaili  3 , Florin Besimi  1 , Nagip Rufati  1
Affiliations
Case Reports

Primary Fallopian Tube Carcinoma: A Case Report and Literature Review

Meral Rexhepi et al. Open Access Maced J Med Sci. .

Abstract

Background: Primary fallopian tube carcinoma (PFTC) is a rare tumour of the female genital tract with an incidence of 0.1-1.8% of all genital malignancies, and it is very difficult to diagnose preoperatively, because of its non-specific symptomatology. In most cases, it is an intraoperative finding or a histopathological diagnosis. It is a tumour that histologically and clinically resembles epithelial ovarian cancer.

Case presentation: We are reporting a case of a 62-year-old, postmenopausal women with primary fallopian tube carcinoma of the right fallopian tube in stage IA. The patient has lower abdominal pain, watery vaginal discharge and repeated episodes of bleeding from the vagina. The clinical and radiological findings suggested a right adnexal tumour with elevated CA-125 levels. Total abdominal hysterectomy, bilateral salpingo-oophorectomy, omentectomy and peritoneal washing were performed. Pathologic confirmation of primary serous cystadenocarcinoma of the right fallopian tube was made. Peritoneal washings were negative for malignancy. FIGO stage was considered as IA, and the patient received no courses of chemotherapy and postoperative radiation because she refused it. Ten months after initial surgery, the patient is alive and in good condition.

Conclusion: Cytoreduction surgery followed by adequate cycles of chemotherapy is an important strategy to improve patients' prognosis.

Keywords: fallopian tube; histopathological diagnosis; intraoperative assessment; post-menopausal female; serous cystadenocarcinoma.

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Figures

Figure 1
Figure 1
Transabdominal ultrasonography showing a multilocular cyst with incomplete septation
Figure 2
Figure 2
Tortuous fallopian tube (up), exophytic, neoplastic white grayish soft lesions (down)
Figure 3
Figure 3
a) HE x 4 Adenocarcinoma tube; b) HE x 10 intact musculature; c) HE x 40 malignant epithelium
Figure 4
Figure 4
a) CK7 x 10 immunostaining positive with CK7 antibody; b) WT1 x 20 immunostaining positive with WT1 antibody; c) P53 x 20 immunostaining positive with P53 antibody
See this image and copyright information in PMC

References

    1. Kalampokas E, Kalampokas T, Tourountous I. Primary fallopian tube carcinoma. Eur J Obstet Gynecol Reprod Biol. 2013;169:155–61. https://doi.org/10.1016/j.ejogrb.2013.03.023 . PMid:23622731. - PubMed
    1. Lau HY, Chen YJ, Yen MS, et al. Primary fallopian tube carcinoma: a clinicopathologic analysis and literature review. J Chin Med Assoc. 2013;76(10):583–7. https://doi.org/10.1016/j.jcma.2013.06.010 . PMid:23890835. - PubMed
    1. Ma Y, Duan W. Clinical and survival analysis of 36 cases of primary fallopian tube carcinoma. World Journal of Surgical Oncology. 2014;12(1):311. https://doi.org/10.1186/1477-7819-12-311 . PMid:25307473. PMCid: PMC4200227. - PMC - PubMed
    1. Pectasides D, Pectasides E, Economopoulos T. Fallopian tube carcinoma: a review. Oncologist. 2006;11(8):902–12. https://doi.org/10.1634/theoncologist.11-8-902 . PMid:16951394. - PubMed
    1. Horng HC, Teng SW, Huang BS, et al. Primary fallopian tube cancer: domestic data and up-to-date review. Taiwan J. Obstet Gynecol. 2014;53(3):287–92. https://doi.org/10.1016/j.tjog.2014.07.003 . PMid:25286779. - PubMed

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