A Population-Based Study of the Incidence of Acute Spinal Cord Infarction

Abstract

Background: There is a paucity of reliable data regarding incidence of acute spinal cord infarction in population-based studies.

Objectives: To determine the incidence of acute spinal cord infarction using a population-based design.

Methods: Medical records and neuroimaging data of all patients with acute spinal cord infarction from Stearns and Benton Counties, Minnesota, between January 1, 2010 and May 31, 2014 were reviewed. Patients with a first-time diagnosis of spinal cord infarction were categorized as primary or secondary depending upon underlying etiology identified. We calculated the incidences of primary and secondary spinal cord infarction adjusted for age and sex based on the 2010 US census (189,093 resident populations).

Results: The age- and sex-adjusted incidence of spinal cord infarction was 3.1 [95% confidence interval (CI) 1.6-7.2] per100,000 person-years. The age- and sex-adjusted incidence of primary and secondary spinal cord infarction was 1.5 [95% CI 0.6-3.6] and 1.6 [95% CI 0.6-3.6] per 100,000 person-years, respectively. The age-adjusted incidences among men and women were 1.5 [95%CI 0.6-3.7] and 4.6 [95% CI 2.2-8.7] per 100,000 person-years, respectively. No case fatality was observed at one month.

Conclusion: We provide incidence rates for acute spinal cord infarction to assist in future studies and resource allocation.

Keywords: Spinal cord infarction; incidence; population-based study; spinal cord ischemia; state-wide survey.