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Editorial
. 2016 Jul 7:8:10.
doi: 10.1186/s41479-016-0010-1. eCollection 2016.

Macrolide resistance in pneumococci-is it relevant?

Allen C Cheng  1   2   3 , Adam W J Jenney  4   3   5
Affiliations
Editorial

Macrolide resistance in pneumococci-is it relevant?

Allen C Cheng et al. Pneumonia (Nathan). .

Abstract

Macrolide antibiotics are widely used for a range of indications, including pneumonia. Both high-level and low-level resistance to macrolides is increasing in pneumococci globally. Macrolide resistance in pneumococci is of limited clinical relevance where ß-lactams remain the mainstay of treatment, such as for moderate/severe pneumonia; however, data suggest that macrolides may not be able to be relied on as monotherapy for serious pneumococcal infections.

Keywords: Antibiotic resistance; Community-acquired pneumonia; Macrolides; Streptococcus pneumoniae.

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