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. 2017 Jul 12;22(1):9-11.
doi: 10.1016/j.chom.2017.06.015.

Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly

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Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly

Robyn S Klein. Cell Host Microbe. .

Abstract

Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections.

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