Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Jul 12;22(1):9-11.
doi: 10.1016/j.chom.2017.06.015.

Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly

Robyn S Klein  1
Affiliations

Dual Blades: The Role of Musashi 1 in Zika Replication and Microcephaly

Robyn S Klein. Cell Host Microbe. .

Abstract

Infection with Zika virus (ZIKV) during pregnancy may cause severe developmental defects in the human brain via unknown mechanisms. In a recent issue of Science, Chavali et al. (2017) identified a neural progenitor cell (NPC)-specific RNA binding protein that may underlie the high levels of ZIKV replication and apoptosis observed in these cells during congenital infections.

PubMed Disclaimer

References

    1. Akiyama BM, Laurence HM, Massey AR, Costantino DA, Xie X, Yang Y, Shi PY, Nix JC, Beckham JD, Kieft JS. Science. 2016;354:1148–1152. - PMC - PubMed
    1. Barbelanne M, Tsang WY. BioMed Res Int. 2014;2014:547986. - PMC - PubMed
    1. Cernescu C, Rojanschi D. Virologie. 1981;32:199–206. - PubMed
    1. Chavali PL, Stojic L, Meredith LW, Joseph N, Nahorski MS, Sanford TJ, Sweeney TR, Krishna BA, Hosmillo M, Firth AE, et al. Science. 2017 Published online June 1, 2017. http://dx.doi.org/10.1126/science.aam9243. - DOI - PMC - PubMed
    1. Dang J, Tiwari SK, Lichinchi G, Qin Y, Patil VS, Eroshkin AM, Rana TM. Cell Stem Cell. 2016;19:258–265. - PMC - PubMed

MeSH terms