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Case Reports
. 2017 Jun 29:9:70-72.
doi: 10.1016/j.idcr.2017.06.012. eCollection 2017.

A rare case of disseminated Sporothrix schenckii with bone marrow involvement in a patient with idiopathic CD4 lymphocytopenia

Kruti J Yagnik  1 , William Paul Skelton 4th  1 , Angela Olson  2 , Cesar A Trillo  2 , Jorge Lascano  2
Affiliations
Case Reports

A rare case of disseminated Sporothrix schenckii with bone marrow involvement in a patient with idiopathic CD4 lymphocytopenia

Kruti J Yagnik et al. IDCases. .

Abstract

Sporothrix schenckii is a pathogen with a predilection for dissemination in immunocompromised individuals, often with HIV. We report a case of disseminated sporotrichosis in an unfortunate 25 year old male (without HIV) who was originally treated for presumed pneumonia. The patient continued to worsen clinically and further work-up eventually revealed Sporothrix schenckii species with involvement of multiple organs including the skin, heart, lungs and bone marrow. Despite treatment with multiple antibacterials and antifungals, he ultimately passed away. This case illustrates the aggressive nature of this disease along with the importance of early/proper diagnosis and treatment.

Keywords: Bone marrow; CD4 lymphocytopenia; Immunocompromised; Sporothrix schenckii.

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Figures

Fig. 1
Fig. 1
Papular rash on chest.
Fig. 2
Fig. 2
Cavitary lesion on high-resolution CT Chest.
Fig. 3
Fig. 3
Skin biopsy (GMS stain) showing fungal forms.
Fig. 4
Fig. 4
Bone marrow biopsy (GMS stain) showing hypocellular bone marrow with fungal elements present .
See this image and copyright information in PMC

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