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Editorial
. 2017 Oct 1;313(4):H687-H689.
doi: 10.1152/ajpheart.00374.2017. Epub 2017 Jul 14.

Uncovering novel roles for matrix metalloproteinases in preeclampsia

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Editorial

Uncovering novel roles for matrix metalloproteinases in preeclampsia

Christopher A Foote et al. Am J Physiol Heart Circ Physiol. .
No abstract available

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Figures

Fig. 1.
Fig. 1.
Plausible model in which hypoxia/oxidative stress in the placenta activates a disintegrin and metalloproteinase-17 (ADAM17), leading to the shedding and activation of TNF-α and the subsequent increased expression/activity of matrix metalloproteinase (MMP)-1 and MMP-7 and likely other MMPs that impair vascular remodeling and promote preeclampsia.

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References

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