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. 1986 May 1;163(5):1325-30.
doi: 10.1084/jem.163.5.1325.

Retinoic acid-induced gene expression in normal and leukemic myeloid cells

M P Murtaugh, O Dennison, J P Stein, P J Davies

Retinoic acid-induced gene expression in normal and leukemic myeloid cells

M P Murtaugh et al. J Exp Med. .

Abstract

Retinoic acid has been shown to induce large accumulations of tissue transglutaminase in cultured myeloid cells. Addition of retinoic acid to mouse resident peritoneal macrophages increased the level of tissue transglutaminase mRNA within 30-60 min. Retinoic acid also increased tissue transglutaminase mRNA levels in human promyelocytic leukemia (HL-60) cells. These studies show that retinoic acid can induce acute alterations in specific gene expression in both normal and leukemic myeloid cells.

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References

    1. Proc Natl Acad Sci U S A. 1972 Jun;69(6):1408-12 - PubMed
    1. Biochemistry. 1979 Nov 27;18(24):5294-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1980 May;77(5):2936-40 - PubMed
    1. J Biol Chem. 1982 Dec 10;257(23):14370-4 - PubMed
    1. J Biol Chem. 1985 Apr 25;260(8):5166-74 - PubMed

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