Porocarcinoma; presentation and management, a meta-analysis of 453 cases
- PMID: 28721214
- PMCID: PMC5499034
- DOI: 10.1016/j.amsu.2017.06.027
Porocarcinoma; presentation and management, a meta-analysis of 453 cases
Abstract
Background: porocarcinoma is a rare sort of skin cancer developing from sweat glands. Its clinical course and management are not well understood.
Objectives: the current meta-analysis is to address the presentation and management of porocarcinoma.
Data sources: Web of Science, PubMed, MEDLINE on OVID and Google scholar were searched for English-language studies published before December 1, 2016.
Results: The review of literature revealed 453 cases. From which 222 (49%) cases were male and female were 231 (51%). The mean age was 67.57 years. The mean duration of presentation was 5.57 years ranging from 4 days to 60 years of age. The most common site of affection is the head and neck (39.9%) followed by lower extremity (33.9%). Mass and nodule are the most common modes of presentation. Metastasis occurred at presentation in 110 (31%) cases. The most common organ to which porocarcinoma metastizes is the nearby lymph node (57.7%).
Conclusions: Porocarcinoma is an aggressive skin cancer. Surgery is the main modality of treatment.
Systematic review registration number: reviewregistry233.
Keywords: Aggressive; Carcinoma; Management; Porocarcinoma; Presentation.
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Further reading
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- Yamamoto Osamu, Haratake Joji, Yokoyama Shigeo, Imayama Shuhei, Asahi Masakazu. A histopathological and ultrastructural study of eccrine porocarcinoma with special reference to its subtypes. Virchows Arch. A Pathol. Anat. 1992;420:395–401. - PubMed
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