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Varicella-zoster virus (chickenpox) is an acute febrile rash illness that was very common in children in the United States before the universal vaccination program existed. Luckily, the varicella-zoster virus is a vaccine-preventable disease. The FDA approves using the live varicella virus vaccine to provide immunity for preventing varicella in individuals 12 months older. This activity reviews the mechanism of action, indications, contraindications, adverse effects of this vaccine, and the front-line personnel involved in preventing the disease.
Gabutti G, Franchi M, Maniscalco L, Stefanati A. Varicella-zoster virus: pathogenesis, incidence patterns and vaccination programs. Minerva Pediatr. 2016 Jun;68(3):213-25.
-
PubMed
Ong CY, Low SG, Vasanwala FF, Baikunje S, Low LL. Varicella infections in patients with end stage renal disease: a systematic review. BMC Nephrol. 2018 Jul 24;19(1):185.
-
PMC
-
PubMed
American Academy of Pediatrics Committee on Infectious Diseases. Prevention of varicella: recommendations for use of varicella vaccines in children, including a recommendation for a routine 2-dose varicella immunization schedule. Pediatrics. 2007 Jul;120(1):221-31.
-
PubMed
Haberthur K, Engelmann F, Park B, Barron A, Legasse A, Dewane J, Fischer M, Kerns A, Brown M, Messaoudi I. CD4 T cell immunity is critical for the control of simian varicella virus infection in a nonhuman primate model of VZV infection. PLoS Pathog. 2011 Nov;7(11):e1002367.
-
PMC
-
PubMed
Walker TY, Elam-Evans LD, Yankey D, Markowitz LE, Williams CL, Mbaeyi SA, Fredua B, Stokley S. National, Regional, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13-17 Years - United States, 2017. MMWR Morb Mortal Wkly Rep. 2018 Aug 24;67(33):909-917.
-
PMC
-
PubMed