Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Subarachnoid Hemorrhage

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Subarachnoid Hemorrhage

Endrit Ziu et al.
Free Books & Documents

Excerpt

Overall, about 20% of strokes are hemorrhagic, with SAH and Intracerebral hemorrhage (ICH) each accounting for 10%. Subarachnoid space is described as a space between the arachnoid membrane and the pia mater. It consists of the cerebrospinal fluid and the blood vessels that supply different areas of the brain. A subarachnoid hemorrhage (SAH) is defined as the accumulation of blood in the space between the arachnoid membrane and the pia mater around the brain referred to as the subarachnoid space. The etiology of SAH can be either nontraumatic (about 85% are secondary to aneurysm rupture) or traumatic in nature. In this review, we shall discuss the various aspects of nontraumatic SAH. Most nontraumatic causes of SAH (~ 85%) are caused by the rupture of an intracranial aneurysm. The remaining 15-20% of patients presenting with SAH do not have a vascular lesion on the initial digital subtraction angiography. Regardless of the cause, a SAH is often a devastating clinical event with substantial mortality and high morbidity among survivors. Prehospital care is critical and involves triaging the patient with attention to the airway, breathing, and circulation to a hospital with neurocritical/neurosurgical expertise. The classic presentation is often a sudden-onset, severe headache typically described as the "worst headache of my life". Treatments are based on randomized controlled studies and prospective cohort studies. A SAH has a prolonged course of illness and is complicated by various factors not limited to seizures, vasospasm, hydrocephalus, and delayed cerebral ischemia (DCI).

PubMed Disclaimer

Conflict of interest statement

Disclosure: Endrit Ziu declares no relevant financial relationships with ineligible companies.

Disclosure: Mahammed Khan Suheb declares no relevant financial relationships with ineligible companies.

Disclosure: Fassil Mesfin declares no relevant financial relationships with ineligible companies.

References

    1. de Rooij NK, Linn FH, van der Plas JA, Algra A, Rinkel GJ. Incidence of subarachnoid haemorrhage: a systematic review with emphasis on region, age, gender and time trends. J Neurol Neurosurg Psychiatry. 2007 Dec;78(12):1365-72. - PMC - PubMed
    1. Ikawa F, Michihata N, Matsushige T, Abiko M, Ishii D, Oshita J, Okazaki T, Sakamoto S, Kurogi R, Iihara K, Nishimura K, Morita A, Fushimi K, Yasunaga H, Kurisu K. In-hospital mortality and poor outcome after surgical clipping and endovascular coiling for aneurysmal subarachnoid hemorrhage using nationwide databases: a systematic review and meta-analysis. Neurosurg Rev. 2020 Apr;43(2):655-667. - PubMed
    1. Schwartz TH, Solomon RA. Perimesencephalic nonaneurysmal subarachnoid hemorrhage: review of the literature. Neurosurgery. 1996 Sep;39(3):433-40; discussion 440. - PubMed
    1. Kowalski RG, Claassen J, Kreiter KT, Bates JE, Ostapkovich ND, Connolly ES, Mayer SA. Initial misdiagnosis and outcome after subarachnoid hemorrhage. JAMA. 2004 Feb 18;291(7):866-9. - PubMed
    1. Gallas S, Tuilier T, Ebrahiminia V, Bartolucci P, Hodel J, Gaston A. Intracranial aneurysms in sickle cell disease: Aneurysms characteristics and modalities of endovascular approach to treat these patients. J Neuroradiol. 2020 May;47(3):221-226. - PubMed

Publication types

LinkOut - more resources