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Book

Hypernatremia

Bhavin Sonani  1 , Srividya Naganathan  2 , Mohammed A. Al-Dhahir  3
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
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Book

Hypernatremia

Bhavin Sonani et al.
Free Books & Documents

Excerpt

Sodium is a dominant cation in extracellular fluid and is necessary for the maintenance of intravascular volume. The human body maintains sodium and water homeostasis by concentrating the urine secondary to the action of antidiuretic hormone (ADH) and increased fluid intake by a powerful thirst response. These mechanisms to protect against developing hypernatremia are impaired in certain vulnerable populations, vasopressin deficiency, or unresponsiveness at the renal tubular level. Hypernatremia is defined as a serum sodium concentration of greater than 145 meq/L.

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Conflict of interest statement

Disclosure: Bhavin Sonani declares no relevant financial relationships with ineligible companies.

Disclosure: Srividya Naganathan declares no relevant financial relationships with ineligible companies.

Disclosure: Mohammed Al-Dhahir declares no relevant financial relationships with ineligible companies.

References

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