Upgrading from iMac to iMicro
- PMID: 28723544
- DOI: 10.1016/j.immuni.2017.07.001
Upgrading from iMac to iMicro
Abstract
In this issue of Immunity, Takata et al. (2017) describe a novel method to differentiate macrophages from iPSCs. These cells, which they call iMacs, are similar to yolk-sac-derived macrophages and are capable of undergoing terminal differentiation into tissue-resident-like macrophages in vitro and in vivo.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Induced-Pluripotent-Stem-Cell-Derived Primitive Macrophages Provide a Platform for Modeling Tissue-Resident Macrophage Differentiation and Function.Immunity. 2017 Jul 18;47(1):183-198.e6. doi: 10.1016/j.immuni.2017.06.017. Immunity. 2017. PMID: 28723550