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Review
. 2017 Oct 12;130(15):1699-1705.
doi: 10.1182/blood-2017-04-778225. Epub 2017 Jul 19.

Racial and ethnic disparities in hematologic malignancies

Kedar Kirtane  1   2 , Stephanie J Lee  1   2
Affiliations
Review

Racial and ethnic disparities in hematologic malignancies

Kedar Kirtane et al. Blood. .

Abstract

Racial and ethnic disparities in patients with solid malignancies have been well documented. Less is known about these disparities in patients with hematologic malignancies. With the advent of novel chemotherapeutics and targeted molecular, cellular, and immunologic therapies, it is important to identify differences in care that may lead to disparate outcomes. This review provides a critical appraisal of the empirical research on racial and ethnic disparities in incidence, survival, and outcomes in patients with hematologic malignancies. The review focuses on patients with acute myeloid leukemia, acute lymphocytic leukemia, multiple myeloma, non-Hodgkin lymphoma, Hodgkin lymphoma, myeloproliferative neoplasms, and myelodysplastic syndrome. The review discusses possible causes of racial and ethnic disparities and also considers future directions for studies to help decrease disparities.

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Conflict of interest statement

Conflict-of-interest disclosure: The authors declare no competing financial interests.

Figures

Figure 1.
Figure 1.
Five-year relative survival for patients with ALL by age group and race from SEER 18 (2000-2014). Non-Hispanic whites were used as the reference group. Hispanic categorization was not mutually exclusive from other race categories. Reported data used unadjusted P values. **P < .001; *P < .05.
Figure 2.
Figure 2.
Conceptual framework for disparities in care for hematologic malignancies.
See this image and copyright information in PMC

Comment in

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