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. 2017 Jul;81(3):231-234.

Maternal and fetal arterial blood gas data in normotensive, singleton, isoflurane anesthetized sheep at 124-126 days of gestation

Claire M Loughran  1 , Matthew W Kemp  1 , Gabrielle C Musk  1
Affiliations

Maternal and fetal arterial blood gas data in normotensive, singleton, isoflurane anesthetized sheep at 124-126 days of gestation

Claire M Loughran et al. Can J Vet Res. 2017 Jul.

Abstract
in English, French

The aim of this case series was to describe the differences between maternal and fetal blood-gas results during anesthesia. Sixteen singleton adult merino ewes weighing 60.1 ± 5.1 kg at 125.7 d (124 to 126 d) gestation were anesthetized. Maternal (radial) and fetal (umbilical) arterial blood gas samples were collected 79 ± 6 min after the start of anesthesia if maternal mean arterial pressure (MAP) was stable and > 65 mmHg. Fetal pH, partial arterial pressure of oxygen (PaO2), glucose, arterial hemoglobin oxygen saturation (SaO2), sodium, and chloride were significantly lower and fetal partial arterial pressure of carbon dioxide (PaCO2), lactate, hematocrit, total hemoglobin, potassium, and calcium were significantly higher than maternal blood-gas values. Fetal pH, PaO2, and BE were lower and fetal lactate was higher than fetal umbilical arterial samples previously reported, which may indicate a non-reassuring fetal status. Further refinement of the ovine experimental model is warranted with fetal monitoring during maternal anesthesia.

L’objectif de l’étude était de décrire les différences dans les résultats d’analyse des gaz sanguins maternel et foetal durant l’anesthésie. Seize brebis mérinos primipares pesant 60,1 ± 5,1 kg à 125,7 j (124 à 126 j) de gestation ont été anesthésiées. Des échantillons de sang artériel maternel (radiale) et foetal (ombilicale) ont été prélevés 79 ± 6 min après le début de l’anesthésie si la pression artérielle moyenne (PAM) maternelle était stable et > 65 mmHg. Pour le sang foetal, les valeurs de pH, de la pression artérielle partielle en oxygène (PaO2), du glucose, de la saturation en oxygène de l’hémoglobine artérielle (SaO2), du sodium, et du chlorure étaient significativement inférieures, et les valeurs de la pression artérielle partielle en dioxyde de carbone (PaCO2), du lactate, de l’hématocrite, de l’hémoglobine totale, du potassium, et du calcium étaient significativement supérieures que celles du sang maternel. Les valeurs foetales du pH, de la PaO2, et de BE étaient plus basses et le lactate foetal étaient plus élevées que les valeurs d’échantillons provenant du sang artériel ombilical foetal rapportées précédemment, ce qui pourrait indiquer un statut foetal non-rassurant. Des améliorations de ce modèle expérimental ovin sont souhaitées avec un suivi foetal durant une anesthésie maternelle.(Traduit par Docteur Serge Messier).

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