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Review
. 2016 Dec 10;7(3):360-366.
doi: 10.1016/j.jtcme.2016.11.003. eCollection 2017 Jul.

Medicinal importance, pharmacological activities, and analytical aspects of hispidulin: A concise report

Kanika Patel  1 , Dinesh Kumar Patel  2
Affiliations
Review

Medicinal importance, pharmacological activities, and analytical aspects of hispidulin: A concise report

Kanika Patel et al. J Tradit Complement Med. .

Abstract

Herbal medicines have been played an important role in the human civilization since very ancient time as a food, cloth, medicine and other aspects. Some of the important drugs in the modern medicine were derived from the natural sources such as aspirin, digitalis, quinine, vincristine, vinblastine etc. Hispidulin (4', 5, 7-trihydroxy-6-methoxyflavone) is a flavones derivative found in plant such as Grindelia argentina, Arrabidaea chica, Saussurea involucrate, Crossostephium chinense, Artemisia and Salvia species. Hispidulin have antioxidant, antifungal, anti-inflammatory, antimutagenic, and antineoplastic properties. So far, various analytical methods have been investigated and developed for detection of hispidulin in the plant materials. Productions of hispidulin through different tissue culture techniques have been also investigated. Present review summarized medicinal uses, pharmacological activities and analytical aspects of hispidulin. From the above mentioned aspects, we can conclude that, this review will be helpful to the researcher in the field of natural product for the development of novel molecule for the treatment of different disorders.

Keywords: Analytical aspects; Herbal medicine; Hispidulin; Medicinal aspects; Pharmacological activities.

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Figures

None
Graphical abstract
Fig. 1
Fig. 1
Chemical structure and overview of hispidulin.
See this image and copyright information in PMC

References

    1. Zheng W., Wang S.Y. Antioxidant activity and phenolic compounds in selected herbs. J Agric Food Chem. 2001;49:5165–5170. - PubMed
    1. Patel D.K., Patel K., Duraiswamy B., Dhanabal S.P. Phytochemical analysis and standardization of Strychnos nux-vomica extract through HPTLC techniques. Asian Pac J Trop Dis. 2012;2:S56–S60.
    1. Talib W.H., Abu Zarga M.H., Mahasneh A.M. Antiproliferative, antimicrobial and apoptosis inducing effects of compounds isolated from Inula viscose. Molecules. 2012;17:3291–3303. - PMC - PubMed
    1. Kumari A., Sharma R.A. A review on Millingtonia hortensis Linn. Int J Pharm Sci Rev Res. 2013;19:85–92.
    1. Mounnissamy V.M., Kavimani S., Balu V., Sankari G., Quine S.D. Anti-nociceptive activity of Cansjera rheedii J. Gmelin (Opiliaceae) Maejo Int J Sci Technol. 2009;3:306–312.

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