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Review
. 2017 Oct;53(5):749-757.
doi: 10.1007/s11262-017-1492-5. Epub 2017 Jul 19.

Strategies and methods for the detection and identification of viral vectors

Thorsten Stellberger  1 , Nina Koehler  1 , Anna Dinkelmeier  1 , Johannes Draxler  1 , Maren Haase  1 , Jessica Hellinckx  1 , Melanie Pavlovic  1 , Ulrich Busch  1 , Armin Baiker  2
Affiliations
Review

Strategies and methods for the detection and identification of viral vectors

Thorsten Stellberger et al. Virus Genes. 2017 Oct.

Abstract

The production and application of viral vectors are frequently performed genetic engineering operations. HIV-1-based lentiviral vectors, AAV2-based, and adenoviral vectors are amongst the most abundant viral vectors utilized for gene delivery. They are generally classified into risk group 1 or 2 (according to EU directive 2000/54/EC on the protection of workers from risks related to exposure to biological agents at work).

Keywords: AAV; Adenovirus; Detection methods; Lentivirus; Viral vector.

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