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. 2017 May;474(1):189-192.
doi: 10.1134/S1607672917030061. Epub 2017 Jul 20.

Kinetics of DNA elongation

V I Bykov  1 , A V Lukovenkov  2 , S D Varfolomeev  1
Affiliations

Kinetics of DNA elongation

V I Bykov et al. Dokl Biochem Biophys. 2017 May.

Abstract

A mathematical model of the DNA elongation stage is proposed, and a formula for calculating the characteristic time of doubling a DNA strand consisting of a large numbers of nucleotides was derived. It is shown that, when the number of nucleotides is greater than 50, it is fair to use a linear dependence of the elongation time on the number of nucleotides. Calculations of the DNA elongation time for a number of organisms are given.

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