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Review
. 2018 Feb;84(2):236-245.
doi: 10.23736/S0375-9393.17.12016-X. Epub 2017 Jul 20.

Machine perfusion in liver transplantation: an essential treatment or just an expensive toy?

Andrea A Schlegel  1   2   3   4 , Marit Kalisvaart  1 , Paolo Muiesan  5   3
Affiliations
Free article
Review

Machine perfusion in liver transplantation: an essential treatment or just an expensive toy?

Andrea A Schlegel et al. Minerva Anestesiol. 2018 Feb.
Free article

Abstract

This review focuses on recent developments in preservation techniques in liver transplantation. First, we discuss mechanisms of organ injury when using high-risk organs, including donation after circulatory death and steatotic grafts and we summarize pathways of ischemia reperfusion injury together with their link to the immune response. Second, we report on improvement strategies of marginal liver grafts by different machine perfusion concepts and summarize perfusion approaches with recent clinical implementation.

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  • Climate change in liver preservation?
    Levesque E, Compagnon P. Levesque E, et al. Minerva Anestesiol. 2018 Feb;84(2):154-156. doi: 10.23736/S0375-9393.17.12397-7. Epub 2017 Oct 4. Minerva Anestesiol. 2018. PMID: 28984106 No abstract available.

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