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Comment
. 2017 Jul 25;9(1):68.
doi: 10.1186/s13073-017-0461-x.

Next-generation sequencing to monitor the spread of antimicrobial resistance

Michael Otto  1
Affiliations
Comment

Next-generation sequencing to monitor the spread of antimicrobial resistance

Michael Otto. Genome Med. .

Abstract

Next-generation sequencing is increasingly being used to monitor current and historic events related to the emergence and spread of antimicrobial resistance. In a recent publication, researchers analyzed the rise of methicillin-resistant Staphylococcus aureus in the 1960s, emphasizing that adaptations conferring antibiotic resistance might pre-date the introduction of novel antibiotic derivatives. Other researchers have evaluated the role of transmission within a healthcare network, using the example of extended-spectrum beta-lactamase-resistant Escherichia coli.Please see related Genome Biology Research article: www.dx.doi.org/10.1186/s13059-017-1252-9 and Genome Medicine Research article: www.dx.doi.org/10.1186/s13073-017-0457-6.

Keywords: Antibiotic resistance; ESBL; Escherichia coli; MRSA; Next-generation sequencing; Staphylococcus aureus.

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Conflict of interest statement

Competing interests

The author declares that he has no competing interests.

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Comment on

References

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