Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Apr-Jun;13(2):55-59.
doi: 10.14797/mdcj-13-2-55.

Hypothyroidism and the Heart

Maja Udovcic  1 , Raul Herrera Pena  1 , Bhargavi Patham  1 , Laila Tabatabai  1 , Abhishek Kansara  1
Affiliations
Review

Hypothyroidism and the Heart

Maja Udovcic et al. Methodist Debakey Cardiovasc J. 2017 Apr-Jun.

Abstract

Hypothyroidism is a commonly encountered clinical condition with variable prevalence. It has profound effects on cardiac function that can impact cardiac contractility, vascular resistance, blood pressure, and heart rhythm. With this review, we aim to describe the effects of hypothyroidism and subclinical hypothyroidism on the heart. Additionally, we attempt to briefly describe how hypothyroid treatment affects cardiovascular parameters.

Keywords: hypothyroidism; subclinical hypothyroidism; thyroid-stimulating hormone; thyroxine.

PubMed Disclaimer

Conflict of interest statement

The authors have completed and submitted the Methodist DeBakey Cardiovascular Journal Conflict of Interest Statement and none were reported.

Figures

Figure 1.
Figure 1.
Effects of hypothyroidism on the heart. Modified from Klein et al. SVR: systemic vascular resistance; BP: blood pressure; PAR: peripheral arterial resistance
Figure 2.
Figure 2.
Management of amiodarone-induced hypothyroidism.
See this image and copyright information in PMC

Comment in

References

    1. Klein I, Danzi S. Thyroid disease and the heart. Circulation. 2007. October 9; 116 15: 1725– 35. - PubMed
    1. Ochs N, Auer R, Bauer DC, . et al. Meta-analysis: subclinical thyroid dysfunction and the risk for coronary heart disease and mortality. Ann Intern Med. 2008. June 3; 148 11: 832– 45. - PubMed
    1. Razvi S, Shakoor A, Vanderpump M, Weaver JU, Pearce SH.. The influence of age on the relationship between subclinical hypothyroidism and ischemic heart disease: a metaanalysis. J Clin Endocrinol Metab. 2008. August; 93 8: 2998– 3007. - PubMed
    1. Jabbar A, Pingitore A, Pearcs SH, Zaman A, Iervasi G, Razvi S.. Thyroid hormones and cardiovascular disease. Nat Rev Cardiol. 2017. January; 14 1: 39– 55. - PubMed
    1. Vargas-Uricoechea H, Bonelo-Perdomo A, Sierra-Torres CH.. Effects of thyroid hormones on the heart. Clin Investig Arterioscler. 2014. Nov-Dec; 26 6: 296– 309. - PubMed

LinkOut - more resources