Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2017 Jun;9(6):1393-1395.
doi: 10.21037/jtd.2017.05.41.

Effects of early administration of acetazolamide on the duration of mechanical ventilation in patients with chronic obstructive pulmonary disease: still far from the truth?

Mabrouk Bahloul  1 , Rania Ammar  1 , Abir Bouattour  1 , Samar Bellil  1 , Hedi Chelly  1 , Anis Chaari  1 , Mounir Bouaziz  1
Affiliations
Editorial

Effects of early administration of acetazolamide on the duration of mechanical ventilation in patients with chronic obstructive pulmonary disease: still far from the truth?

Mabrouk Bahloul et al. J Thorac Dis. 2017 Jun.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Reasons of acetazolamide (ACTZ) inefficacy in patients with severe exacerbation of chronic obstructive pulmonary disease requiring mechanical ventilation.
See this image and copyright information in PMC

Comment on

References

    1. Rialp Cervera G, Raurich Puigdevall JM, Morán Chorro I, et al. Effects of early administration of acetazolamide on the duration of mechanical ventilation in patients with chronic obstructive pulmonary disease or obesity-hypoventilation syndrome with metabolic alkalosis. A randomized trial. Pulm Pharmacol Ther 2017. [Epub ahead of print]. 10.1016/j.pupt.2017.03.002 - DOI - PubMed
    1. Alp C, Özsoy Ş, Alp NA, et al. Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI. J Enzyme Inhib Med Chem 2012;27:818-24. 10.3109/14756366.2011.617745 - DOI - PubMed
    1. Bahloul M, Chaari A, Tounsi A, et al. Impact of acetazolamide use in severe exacerbation of chronic obstructive pulmonary disease requiring invasive mechanical ventilation. Int J Crit Illn Inj Sci 2015;5:3-8. 10.4103/2229-5151.152296 - DOI - PMC - PubMed
    1. Bahloul M, Chtara K, Chelly H, et al. Acetazolamide use in severe COPD exacerbations requiring invasive mechanical ventilation: impact on duration of mechanical ventilation. J Thorac Dis 2016;8:762-4. 10.21037/jtd.2016.03.65 - DOI - PMC - PubMed
    1. Heming N, Faisy C, Urien S. Population pharmacodynamic model of bicarbonate response to acetazolamide in mechanically ventilated chronic obstructive pulmonary disease patients. Crit Care 2011;15:R213. 10.1186/cc10448 - DOI - PMC - PubMed

LinkOut - more resources