Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Sep 21;1(4):205-215.
doi: 10.1016/j.adro.2016.09.002. eCollection 2016 Oct-Dec.

Oncoplastic breast surgery in the setting of breast-conserving therapy: A systematic review

Affiliations
Review

Oncoplastic breast surgery in the setting of breast-conserving therapy: A systematic review

Jennifer J Yoon et al. Adv Radiat Oncol. .

Abstract

Breast-conserving therapy (BCT), or breast-conserving surgery with adjuvant radiation therapy, has become a standard treatment alternative to mastectomy for women with early-stage breast cancer after many long-term studies have reported comparable rates of overall survival and local control. Oncoplastic breast surgery in the setting of BCT consists of various techniques that allow for an excision with a wider margin and a simultaneous enhancement of cosmetic sequelae, making it an ideal breast cancer surgery. Because of the parenchymal rearrangement that is routinely involved in oncoplastic techniques, however, the targeted tissue can be relocated, thus posing a challenge to localize the tumor bed for radiation planning. The goals of this systematic review are to address the challenges, outcomes, and cosmesis of oncoplastic breast surgery in the setting of BCT.

PubMed Disclaimer

References

    1. van Dongen J.A., Voogd A.C., Fentiman I.S. Long-term results of a randomized trial comparing breast-conserving therapy with mastectomy: European Organization for Research and Treatment of Cancer 10801 trial. J Natl Cancer Inst. 2000;92(14):1143–1150. - PubMed
    1. Veronesi U., Cascinelli N., Mariani L. Twenty-year follow-up of a randomized study comparing breast-conserving surgery with radical mastectomy for early breast cancer. N Engl J Med. 2002;347(16):1227–1232. - PubMed
    1. Asgeirsson K.S., Rasheed T., McCulley S.J., Macmillan R.D. Oncological and cosmetic outcomes of oncoplastic breast conserving surgery. Eur J Surg Oncol. 2005;31(8):817–823. - PubMed
    1. Engel J., Kerr J., Schlesinger-Raab A., Sauer H., Holzel D. Quality of life following breast-conserving therapy or mastectomy: results of a 5-year prospective study. Breast J. 2004;10(3):223–231. - PubMed
    1. Fisher B., Anderson S., Bryant J. Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancer. N Eng J Med. 2002;347(16):1233–1241. - PubMed

LinkOut - more resources