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Review
. 2017 Sep;19(9):31.
doi: 10.1007/s11940-017-0468-z.

CADASIL: Treatment and Management Options

Anna Bersano  1 , Gloria Bedini  2 , Joshua Oskam  3 , Caterina Mariotti  4 , Franco Taroni  4 , Silvia Baratta  4 , Eugenio Agostino Parati  5
Affiliations
Review

CADASIL: Treatment and Management Options

Anna Bersano et al. Curr Treat Options Neurol. 2017 Sep.

Abstract

CADASIL is a life-threatening and disabling disease. Despite the progress achieved so far, no therapies able to limit the disease progression have been found and only empiric treatments can be employed to relieve the main disease symptoms. Further in vivo studies as well as data aggregation and multi-centre controlled clinical trials are needed to confirm the emerging findings in order to identify evidence-based therapies for CADASIL.

Keywords: CADASIL; NOTCH3 gene; Pathogenesis; Therapy.

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