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. 2017 Jul 25;318(4):381-382.
doi: 10.1001/jama.2017.8543.

Cascade Screening for Familial Hypercholesterolemia and the Use of Genetic Testing

Joshua W Knowles  1 , Daniel J Rader  2 , Muin J Khoury  3
Affiliations

Cascade Screening for Familial Hypercholesterolemia and the Use of Genetic Testing

Joshua W Knowles et al. JAMA. .
No abstract available

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Conflict of interest statement

Conflict of Interest Disclosures:

The author has completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Knowles reports grants paid to the institution from the American Heart Association and Amgen. No other disclosures were reported.

Figures

Figure.
Figure.. Process From Case Identification to Cascade Screening
Proband identification can also occur through childhood immunization visits, systematic lipid testing (eg, testing all employees in an organization), or recommended lipid testing (eg, universal screening for adults). Cascade screening begins once the proband has been identified. Next, several steps of cascade screening are needed to identify all patients with familial hypercholesterolemia (FH). Color of shaded segment for FH indicates the cascade cycle during which the affected individual was identified. a Source, Safarova et al.
See this image and copyright information in PMC

References

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