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Comment
. 2017 Aug;29(8):1800-1802.
doi: 10.1105/tpc.17.00356. Epub 2017 Jul 26.

The BIF Domain in Plant bHLH Proteins Is an ACT-Like Domain

Antje Feller  1 , Ling Yuan  2   3 , Erich Grotewold  4
Affiliations
Comment

The BIF Domain in Plant bHLH Proteins Is an ACT-Like Domain

Antje Feller et al. Plant Cell. 2017 Aug.
No abstract available

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Figures

Figure 1.
Figure 1.
Sequence and Structure Comparison of Maize R (represented by ZmLc) and AtDYT1. (A) Alignment of amino acids 525 to 610 of ZmLc (R family member) and amino acids 122 to 207 of AtDYT1 was created by the ClustalW Sequence Alignment Program v1.83 (http://www.genome.jp/tools/clustalw/) and displayed with Expasy Boxshade (http://embnet.vital-it.ch/software/BOX_form.html). Highly conserved amino acids are indicated with black or purple boxes, while gray boxes indicate less conserved ones. Orange-colored amino acids indicate the beginning and end of the structure in (B). The secondary structure was analyzed with the Predictprotein secondary structure prediction program (www.predictprotein.org); blue arrows indicate β-sheets and green cylinders α-helices. (B) The 3D structures of the protein sequences depicted in (A) for ZmLc (left) and AtDYT1 (right) were predicted using the Phyre2 Protein Homology/Analogy Recognition Engine V2.0, followed by in-depth analysis of model quality using Phyre Investigator (Kelley et al., 2015). For both proteins, the library entry d1u8sa2, which corresponds to the ACT-like superfamily ferredoxin-like fold of the glycine-cleavage system transcriptional repressor, was used by Phyre2 to model the 3D structures. Phyre2 was used to perform conservation analyses of each amino acid; those shown in red correspond to high and those in blue to low conservation with respect to d1u8sa2. The dashed line at the bottom of both structures represents regions with undetermined conformation.
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References

    1. Anantharaman V., Koonin E.V., Aravind L. (2001). Regulatory potential, phyletic distribution and evolution of ancient, intracellular small-molecule-binding domains. J. Mol. Biol. 307: 1271–1292. - PubMed
    1. Aravind L., Koonin E.V. (1999). Gleaning non-trivial structural, functional and evolutionary information about proteins by iterative database searches. J. Mol. Biol. 287: 1023–1040. - PubMed
    1. Chantranupong L., Scaria S.M., Saxton R.A., Gygi M.P., Shen K., Wyant G.A., Wang T., Harper J.W., Gygi S.P., Sabatini D.M. (2016). The CASTOR proteins are arginine sensors for the mTORC1 pathway. Cell 165: 153–164. - PMC - PubMed
    1. Chipman D.M., Shaanan B. (2001). The ACT domain family. Curr. Opin. Struct. Biol. 11: 694–700. - PubMed
    1. Cui J., You C., Zhu E., Huang Q., Ma H., Chang F. (2016). Feedback regulation of DYT1 by interactions with downstream bHLH factors promotes DYT1 nuclear localization and anther development. Plant Cell 28: 1078–1093. - PMC - PubMed

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