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Case Reports
. 2017 May 5:27:11.
doi: 10.11604/pamj.2017.27.11.12418. eCollection 2017.

Chondroblastic osteosarcoma of the distal tibia: a rare case report

Aymen Ben Fredj  1 , Lassaad Hassini  1 , Aymen Fekih  1 , Mohamed Allagui  1 , Issam Aloui  1 , Abderrazek Abid  1
Affiliations
Case Reports

Chondroblastic osteosarcoma of the distal tibia: a rare case report

Aymen Ben Fredj et al. Pan Afr Med J. .

Abstract

Chondroblastic osteosarcoma, representing about 25% of osteosarcoma, is a fatal primary malignancy of the skeleton if not diagnosed and treated appropriately. It most commonly occurs in the long bones of the extremities near the metaphyseal growth plates. In this report, we describe the occurrence of chondroblastic osteosarcoma involving the left distal tibia in a 14-year-old male. The diagnosis was confirmed by the histological examination of a surgical biopsy. The patient was treated by both surgery and neoadjuvant chemotherapy. No recurrence was noted at 3 years of follow-up. To our knowledge, only two cases describing chondroblastic osteosarcoma of the distal tibia had been reported through English medical literature. Therefore, the aim of our article is to make the clinician aware of this rare clinical presentation and also to provide a comprehensive review of the literature related to this uncommon malignant tumour.

Keywords: Osteosarcoma; chondroblastic; tibia.

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Figures

Figure 1
Figure 1
(A,B) plain radiographs showing a metaphyseal osteolytic lesion of the distal left tibia; (C,D) MRI, an extension to the adjacent soft tissue and no epiphyseal involvement
Figure 2
Figure 2
(A) per operative aspect; (B) a wide resection of tibia and fibula along 12 cm from the tibio-talar joint performed with a tumour free margin of 3 cm; (C,D) post-operative plain radiographs
Figure 3
Figure 3
(A, B) plain radiographs post reconstruction
Figure 4
Figure 4
(A, B) plain radiographs after osteosynthesis with plate
See this image and copyright information in PMC

References

    1. Picci P. Osteosarcoma (osteogenic sarcoma) Orphanet J Rare Dis. 2007;23:2–6. - PMC - PubMed
    1. VandenBussche CJ, Sathiyamoorthy S, Wakely PE, Jr, Ali SZ. Chondroblastic osteosarcoma: cytomorphologic characeteristics and differential diagnosis on FNA. Cancer Cytopathol. 2016;124(7):493–500. - PubMed
    1. Fox C, Husain ZS, Shah MB, Lucas DR, Saleh HA. Chondroblastic osteosarcoma of the cuboid: a literature review and report of a rare case. J Foot Ankle Surg. 2009;48(3):388–93. - PubMed
    1. Scudday TS, Danisa OA, Zuckerman LM. Management of pelvic chondroblastic osteosarcoma after urgent decompression-A report of 2 cases. J Orthop Case Rep. 2016;6(1):72–5. - PMC - PubMed
    1. Jerome TJ, Varghese M, Sankaran B, Thomas S, Thirumagal SK. Tibial chondroblastic osteosarcoma-case report. Foot Ankle Surg. 2009;15(1):33–9. - PubMed

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