An Exploration of Phytochemicals from Simaroubaceae
- PMID: 28749102
- PMCID: PMC5648376
- DOI: 10.22034/APJCP.2017.18.7.1765
An Exploration of Phytochemicals from Simaroubaceae
Abstract
Natural products such as plants, animals and minerals have been the basis of treatment of human diseases. Herbal remedies have been used for the treatment of many ailments. Many compounds have been derived from the plant species mentioned in the ancient texts of Indian system of medicine for the treatment of a number of ailments. The R and D thrust in the pharmaceutical sector is focused on development of new drugs, innovative/indigenous processes for known drugs and development of plant based drugs through investigation of leads from the traditional systems of medicine. The family Simaroubaceae is grouped in the order Rutales, is known to have a diverse range of secondary metabolites. Plants from this family are used as medicine to cure cancer and many other diseases. Isolation of diverse chemical compounds from Simaroubaceae on its stem bark, root bark and leaves have been reported. In this review, we are analysing with the chemical constituents of family Simaroubaceae.
Keywords: Simaroubaceae; Quassinoids; Polyphenols.
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References
-
- Barbosa R, Braz-Filho I. Vieira Chemical constituents of plants from the genus Simaba (Simaroubaceae) Chem Biodivers. 2011;8:2163–78. - PubMed
-
- Bentley R. Secondary metabolite biosynthesis: the first century. Crit Rev Biotech. 1999;19:1–40. - PubMed
-
- Bhattacharjee SG, Gupta P, Bhattacharya A, et al. Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert antileishmanial activity. J Antimicrob Chemother. 2008;63:317–24. - PubMed