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Review
. 2017 Jul 27;6(8):76.
doi: 10.3390/jcm6080076.

Long-Term Effects of Pregnancy Complications on Maternal Health: A Review

Affiliations
Review

Long-Term Effects of Pregnancy Complications on Maternal Health: A Review

Ran Neiger. J Clin Med. .

Abstract

Background: Most pregnancy-related medical complications appear to resolve at delivery or shortly thereafter. Common examples are preterm labor, placental abruption, preeclampsia, and gestational diabetes. Women who developed such complications are known to be at increased risk of developing similar complications in future pregnancies. It has recently become evident that these women are at an increased risk of long term medical complications. Methods: A search through scientific publications in English regarding the association of obstetric complications and long-term maternal illness. Results: There is a clear association between various obstetric complications and long-term effects on maternal health. Conclusions: Women with a history of adverse pregnancy outcomes are at increased risk of cardiovascular and metabolic diseases later in life. Data increasingly links maternal vascular, metabolic, and inflammatory complications of pregnancy with an increased risk of vascular disease in later life.

Keywords: gestational diabetes; long-term effects; preeclampsia; pregnancy complications; preterm labor.

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Conflict of interest statement

The author declares no conflict of interest.

References

    1. Davey­Smith G., Harding S., Rosato M. Relation between infants’ birth weight and mothers’ mortality: Prospective observational study. BMJ. 2000;320:839–840. - PMC - PubMed
    1. Smith G.C.S., Pell J.P., Walsh D. Pregnancy complications and maternal risk of ischaemic heart disease: A retrospective cohort study of 129,290 births. Lancet. 2001;357:2002–2006. doi: 10.1016/S0140-6736(00)05112-6. - DOI - PubMed
    1. Sattar N., Greer I.A. Pregnancy complications and maternal cardiovascular risk: Opportunities for intervention and screening? BMJ. 2002;325:157–160. doi: 10.1136/bmj.325.7356.157. - DOI - PMC - PubMed
    1. Magnussen E.B., Vatten L.J., Lund-Nilsen T.I., Salvesen K.A., Davey Smith G., Romundstad P.R. Prepregnancy cardiovascular risk factors as predictors of preeclampsia: Population based cohort study. BMJ. 2007;335:978. doi: 10.1136/bmj.39366.416817.BE. - DOI - PMC - PubMed
    1. Brosens I., Pijnenborg R., Vercruysse L., Romero R. The “Great Obstetrical Syndromes” are associated with disorders of deep placentation. Am. J. Obstet. Gynecol. 2011;204:193–201. doi: 10.1016/j.ajog.2010.08.009. - DOI - PMC - PubMed

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