Towards Improved Translational Stroke Research: Progress and Perspectives of the Recent National Institute of Neurological Disorders and Stroke Consensus Group Meeting

Charlotte Zerna¹, Michael D Hill², Johannes Boltze¹

Affiliations

¹ From the Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, AB, Canada (C.Z.); and Department of Translational Medicine and Cell Technology, Fraunhofer Research Institution for Marine Biotechnology and Institute for Medical and Marine Biotechnology, University of Lübeck, Germany (M.D.H., J.B.).
² From the Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, AB, Canada (C.Z.); and Department of Translational Medicine and Cell Technology, Fraunhofer Research Institution for Marine Biotechnology and Institute for Medical and Marine Biotechnology, University of Lübeck, Germany (M.D.H., J.B.). michael.hill@ucalgary.ca.

PMID: 28751553
DOI: 10.1161/STROKEAHA.117.017906

Editorial

Towards Improved Translational Stroke Research: Progress and Perspectives of the Recent National Institute of Neurological Disorders and Stroke Consensus Group Meeting

Charlotte Zerna et al. Stroke. 2017 Sep.

. 2017 Sep;48(9):2341-2342.

doi: 10.1161/STROKEAHA.117.017906. Epub 2017 Jul 27.

Authors

Charlotte Zerna¹, Michael D Hill², Johannes Boltze¹

Affiliations

¹ From the Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, AB, Canada (C.Z.); and Department of Translational Medicine and Cell Technology, Fraunhofer Research Institution for Marine Biotechnology and Institute for Medical and Marine Biotechnology, University of Lübeck, Germany (M.D.H., J.B.).
² From the Calgary Stroke Program, Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, AB, Canada (C.Z.); and Department of Translational Medicine and Cell Technology, Fraunhofer Research Institution for Marine Biotechnology and Institute for Medical and Marine Biotechnology, University of Lübeck, Germany (M.D.H., J.B.). michael.hill@ucalgary.ca.

PMID: 28751553
DOI: 10.1161/STROKEAHA.117.017906

No abstract available

Keywords: Editorials; animal models; clinical translation; end point selection; predictive value; study design; translational stroke research.

PubMed Disclaimer

Comment in

High Appraisal of Methodological Quality of Basic Science Articles Published in Stroke.
Schäbitz WR, Minnerup J, Fisher M, Aronowski J. Schäbitz WR, et al. Stroke. 2017 Sep;48(9):2337-2338. doi: 10.1161/STROKEAHA.117.017717. Epub 2017 Jul 27. Stroke. 2017. PMID: 28751555 No abstract available.

Comment on

Translational Stroke Research: Vision and Opportunities.
Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, Furie KL, Hemmen TM, Iadecola C, Jakeman LB, Janis S, Jauch EC, Johnston KC, Kochanek PM, Kohn H, Lo EH, Lyden PD, Mallard C, McCullough LD, McGavern LM, Meschia JF, Moy CS, Perez-Pinzon MA, Ramadan I, Savitz SI, Schwamm LH, Steinberg GK, Stenzel-Poore MP, Tymianski M, Warach S, Wechsler LR, Zhang JH, Koroshetz W. Bosetti F, et al. Stroke. 2017 Sep;48(9):2632-2637. doi: 10.1161/STROKEAHA.117.017112. Epub 2017 Jul 27. Stroke. 2017. PMID: 28751554 Free PMC article. Review. No abstract available.

Cited by

Variability of functional outcome measures used in animal models of stroke and vascular cognitive impairment - a review of contemporary studies.
Hietamies TM, Ostrowski C, Pei Z, Feng L, McCabe C, Work LM, Quinn TJ. Hietamies TM, et al. J Cereb Blood Flow Metab. 2018 Nov;38(11):1872-1884. doi: 10.1177/0271678X18799858. Epub 2018 Sep 11. J Cereb Blood Flow Metab. 2018. PMID: 30203705 Free PMC article. Review.
The Need for New Biomarkers to Assist with Stroke Prevention and Prediction of Post-Stroke Therapy Based on Plasma-Derived Extracellular Vesicles.
Driga MP, Catalin B, Olaru DG, Slowik A, Plesnila N, Hermann DM, Popa-Wagner A. Driga MP, et al. Biomedicines. 2021 Sep 15;9(9):1226. doi: 10.3390/biomedicines9091226. Biomedicines. 2021. PMID: 34572411 Free PMC article. Review.
Are researchers moving away from animal models as a result of poor clinical translation in the field of stroke? An analysis of opinion papers.
Pound P, Ram R. Pound P, et al. BMJ Open Sci. 2020 Feb 24;4(1):e100041. doi: 10.1136/bmjos-2019-100041. eCollection 2020. BMJ Open Sci. 2020. PMID: 35047687 Free PMC article.
Can prospective systematic reviews of animal studies improve clinical translation?
Pound P, Ritskes-Hoitinga M. Pound P, et al. J Transl Med. 2020 Jan 9;18(1):15. doi: 10.1186/s12967-019-02205-x. J Transl Med. 2020. PMID: 31918734 Free PMC article.
Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives.
Kuriakose D, Xiao Z. Kuriakose D, et al. Int J Mol Sci. 2020 Oct 15;21(20):7609. doi: 10.3390/ijms21207609. Int J Mol Sci. 2020. PMID: 33076218 Free PMC article. Review.

Publication types

Actions
Actions
Actions

MeSH terms

Actions
Actions
Actions
Actions
Actions
Actions
Actions

Grants and funding

CIHR/Canada

LinkOut - more resources

Full Text Sources
Other Literature Sources
- scite Smart Citations

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

Towards Improved Translational Stroke Research: Progress and Perspectives of the Recent National Institute of Neurological Disorders and Stroke Consensus Group Meeting

Affiliations

Towards Improved Translational Stroke Research: Progress and Perspectives of the Recent National Institute of Neurological Disorders and Stroke Consensus Group Meeting

Authors

Affiliations

Comment in

Comment on

Similar articles

Cited by

Publication types

MeSH terms

Grants and funding

LinkOut - more resources

Full Text Sources

Other Literature Sources