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Review
. 2017 Jul 7:6:1084.
doi: 10.12688/f1000research.11133.1. eCollection 2017.

Recent advances in understanding eosinophil biology

Amy Klion  1
Affiliations
Review

Recent advances in understanding eosinophil biology

Amy Klion. F1000Res. .

Abstract

With the advent of novel therapies targeting eosinophils, there has been renewed interest in understanding the basic biology of this unique cell. In this context, murine models and human studies have continued to highlight the role of the eosinophil in homeostatic functions and immunoregulation. This review will focus on recent advances in our understanding of eosinophil biology that are likely to have important consequences on the development and consequences of eosinophil-targeted therapies. Given the breadth of the topic, the discussion will be limited to three areas of interest: the eosinophil life cycle, eosinophil heterogeneity, and mechanisms of cell-cell communication.

Keywords: cell-cell communication; eosinophils; heterogeneity; life cycle.

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Conflict of interest statement

Competing interests: The author declares that she has no competing interests.No competing interests were disclosed.No competing interests were disclosed.

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