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Case Reports
. 2017 Jul 18:14:45-47.
doi: 10.1016/j.eucr.2017.06.016. eCollection 2017 Sep.

Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype

Pieter D'hulst  1 , Jochen Darras  1 , Steven Joniau  2 , Pieter Mattelaer  1 , Linsey Winne  3 , Diederik Ponette  1
Affiliations
Case Reports

Two-Stage Urethroplasty with Buccal Mucosa for Penoscrotal Hypospadias Reconstruction in a Male with a 46,XX Karyotype

Pieter D'hulst et al. Urol Case Rep. .

Abstract

We present a case regarding a 32-year old African male with penoscrotal hypospadias, left cryptorchidism and a left inguinal hernia. There were moderate masculinization characteristics. He underwent a Lichtenstein hernia repair with perioperative biopsies of the left inguinal testis and epididymis. Microscopic examination showed a Sertoli-only left testis with Leydig-cell hyperplasia and the left epididymis consisted of ovarian tissue with corpora albicantia and maturing follicles. Endocrinological evaluation showed a sex-determining region Y (SRY) negative 46,XX karyotype. We successfully performed a two-stage urethroplasty with buccal mucosa graft to reconstruct his penoscrotal hypospadias.

Keywords: 46,XX testicular disorder of sex development; Cryptorchidism; Hypospadias; Urethroplasty.

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Figures

Figure 1
Figure 1
Status at the time of the second stage urethroplasty: nicely healed buccal mucosa graft.
Figure 2
Figure 2
Tubularization of the BMG into a neo-urethra.
Figure 3
Figure 3
Final result after closure.
See this image and copyright information in PMC

References

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