Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986 Sep;83(17):6238-40.
doi: 10.1073/pnas.83.17.6238.

The pseudopterosins: anti-inflammatory and analgesic natural products from the sea whip Pseudopterogorgia elisabethae

S A Look, W Fenical, R S Jacobs, J Clardy

The pseudopterosins: anti-inflammatory and analgesic natural products from the sea whip Pseudopterogorgia elisabethae

S A Look et al. Proc Natl Acad Sci U S A. 1986 Sep.

Abstract

The Caribbean sea whip Pseudopterogorgia elisabethae (Octocorallia, Cnidaria) has been found to contain the pseudopterosins, a newly described class of natural products, which have been characterized as diterpene-pentoseglycosides. The pseudopterosins possess anti-inflammatory and analgesic properties that exceed, in our assays, the potencies of existing drugs such as indomethacin. As anti-inflammatory agents, the pseudopterosins appear to modify the arachidonic acid cascade by an as yet undefined mechanism of pharmacological action.

PubMed Disclaimer

References

    1. J Pharmacol Exp Ther. 1959 Mar;125(3):237-40 - PubMed
    1. Fed Proc. 1981 Jan;40(1):26-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1985 Jan;82(2):604-7 - PubMed
    1. Experientia. 1984 Sep 15;40(9):931-3 - PubMed
    1. Science. 1981 Jun 26;212(4502):1512-4 - PubMed

Publication types

MeSH terms