Novel use of porcine extracellular matrix in recurrent stricture following repair of tracheoesophageal fistula

Abstract

Anastomotic stricture is a common complication following repair of esophageal atresia (EA). Many factors are thought to contribute to stricture formation and a variety of management techniques have been developed. In this case report, we describe the treatment of a recurrent anastomotic stricture following repair of long-gap esophageal atresia. Porcine bladder extracellular matrix (ECM) was mounted on a stent and delivered endoscopically to the site of recurrent stricture. An appropriate positioning was confirmed using direct endoscopic visualization and intra-operative fluoroscopy. The patient recovered well with persistent radiographic and functional improvements in previous stricture.

Keywords: Anastomotic stricture; Endoscopy; Esophageal atresia; Extracellular matrix; MatriStem; Recurrent esophageal stricture; Tracheoesophageal fistula.