Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Aug:207:239-247.
doi: 10.1016/j.vetmic.2017.07.004. Epub 2017 Jul 5.

Identification and genetic characterization of equine hepaciviruses in Italy

Gabriella Elia  1 , Gianvito Lanave  2 , Eleonora Lorusso  2 , Antonio Parisi  3 , Nicola Cavaliere  3 , Giovanni Patruno  4 , Calogero Terregino  5 , Nicola Decaro  2 , Vito Martella  2 , Canio Buonavoglia  2
Affiliations

Identification and genetic characterization of equine hepaciviruses in Italy

Gabriella Elia et al. Vet Microbiol. 2017 Aug.

Abstract

Viruses similar to human hepatitis C virus, hepaciviruses, have been identified in various animal species. Equine hepacivirus (EqHV) is the closest relative of human hepaciviruses. Although detected worldwide, information on EqHV epidemiology, genetic diversity and pathogenicity is still limited. In this study we investigated the prevalence and genetic diversity of EqHV in Italian equids. The RNA of EqHV was detected in 91/1932 sera (4.7%) whilst it was not detectable in 134 donkey sera screened by a TaqMan-based quantitative assay. Upon sequencing and phylogenetic analysis of genomic portions located in the NS5B, 5'UTR and NS3 genes, the Italian EqHV strains segregated into two distinct clades that are also co-circulating globally, without apparent geographic restrictions.

Keywords: Characterization; Epidemiology; Hepacivirus; Horse.

PubMed Disclaimer

LinkOut - more resources