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Comment
. 2017 Aug 1;196(3):258-260.
doi: 10.1164/rccm.201701-0143ED.

Leveraging Transcriptomics to Disentangle Sepsis Heterogeneity

Hector R Wong  1   2 , John C Marshall  3
Affiliations
Comment

Leveraging Transcriptomics to Disentangle Sepsis Heterogeneity

Hector R Wong et al. Am J Respir Crit Care Med. .
No abstract available

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References

    1. Marshall JC. Why have clinical trials in sepsis failed? Trends Mol Med. 2014;20:195–203. - PubMed
    1. Cohen J, Vincent JL, Adhikari NK, Machado FR, Angus DC, Calandra T, Jaton K, Giulieri S, Delaloye J, Opal S, et al. Sepsis: a roadmap for future research. Lancet Infect Dis. 2015;15:581–614. - PubMed
    1. Prescott HC, Calfee CS, Thompson BT, Angus DC, Liu VX. Toward smarter lumping and smarter splitting: rethinking strategies for sepsis and acute respiratory distress syndrome clinical trial design. Am J Respir Crit Care Med. 2016;194:147–155. - PMC - PubMed
    1. Marshall JC. The PIRO (predisposition, insult, response, organ dysfunction) model: toward a staging system for acute illness. Virulence. 2014;5:27–35. - PMC - PubMed
    1. Maslove DM, Wong HR. Gene expression profiling in sepsis: timing, tissue, and translational considerations. Trends Mol Med. 2014;20:204–213. - PMC - PubMed