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. 2017 Dec;116(8):969-982.
doi: 10.1002/jso.24774. Epub 2017 Aug 2.

Personalizing prognosis in colorectal cancer: A systematic review of the quality and nature of clinical prognostic tools for survival outcomes

Alyson L Mahar  1 , Carolyn Compton  2   3 , Susan Halabi  4 , Kenneth R Hess  5   6 , Martin R Weiser  7 , Patti A Groome  1
Affiliations

Personalizing prognosis in colorectal cancer: A systematic review of the quality and nature of clinical prognostic tools for survival outcomes

Alyson L Mahar et al. J Surg Oncol. 2017 Dec.

Abstract

Integrating diverse types of prognostic information into accurate, individualized estimates of outcome in colorectal cancer is challenging. Significant heterogeneity in colorectal cancer prognostication tool quality exists. Methodology is incompletely or inadequately reported. Evaluations of the internal or external validity of the prognostic model are rarely performed. Prognostication tools are important devices for patient management, but tool reliability is compromised by poor quality. Guidance for future development of prognostication tools in colorectal cancer is needed.

Keywords: clinical prediction tool; colorectal neoplasms; nomogram; prognosis.

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Figures

Figure 1
Figure 1
Search results for clinical prognostic tools and their validation
Figure 2
Figure 2
Prognostic factors used in clinical prediction tools targeted at decision-making and prognosis in patients with colorectal cancer and liver metastases
See this image and copyright information in PMC

Comment in

  • The prognosis for prognostic tools.
    Greene FL. Greene FL. J Surg Oncol. 2017 Dec;116(8):983. doi: 10.1002/jso.24773. Epub 2017 Aug 2. J Surg Oncol. 2017. PMID: 28767124 No abstract available.

References

    1. Gunderson LL, Haller DG, Martenson JA, et al. Impact of T and N stage and treatment on survival and relapse in adjuvant rectal cancer: a pooled analysis. J Clin Oncol. 2004;22:1785–1796. - PubMed
    1. Gunderson LL, Jessup JM, Sargent DJ, et al. Revised tumor and node categorization for rectal cancer based on surveillance, epidemiology, and end results and rectal pooled analysis outcomes. J Clin Oncol. 2010;28:256–263. - PMC - PubMed
    1. Gunderson LL, Jessup JM, Sargent DJ, et al. Revised TN categorization for colon cancer based on national survival outcomes data. J Clin Oncol. 2010;28:264–271. - PMC - PubMed
    1. Edge SB. AJCC Cancer 7th Edition Staging Manual. New York: Springer; 2010.
    1. Haq AI, Schneeweiss J, Kalsi V, Arya M. The Dukes staging system: a cornerstone in the clinical management of colorectal cancer. Lancet Oncol. 2009;10:1128–2045. (1109)70157–70153. - PubMed

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