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Comment
. 2017 Aug 1;26(2):284-285.
doi: 10.1016/j.cmet.2017.07.015.

Holding Onto Youth

Alain Dagher  1 , Bratislav Misic  2
Affiliations
Comment

Holding Onto Youth

Alain Dagher et al. Cell Metab. .

Abstract

Aerobic glycolysis (AG), the synthesis of lactate despite the presence of oxygen, has been implicated in the growth of cancer cells, synaptic development, and brain plasticity. In this issue of Cell Metabolism, Goyal et al. (2017) demonstrate that AG declines with age in the human brain, disappearing almost completely by age 60.

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  • Loss of Brain Aerobic Glycolysis in Normal Human Aging.
    Goyal MS, Vlassenko AG, Blazey TM, Su Y, Couture LE, Durbin TJ, Bateman RJ, Benzinger TL, Morris JC, Raichle ME. Goyal MS, et al. Cell Metab. 2017 Aug 1;26(2):353-360.e3. doi: 10.1016/j.cmet.2017.07.010. Cell Metab. 2017. PMID: 28768174 Free PMC article.

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